Malware samples can use various techniques to detect whether they are being executed in an automated malware analysis environment such as they are capable of detecting a sandbox, a debugger and a virtual environment.
On the positive side there are plenty of automated malware analysis services on the Internet, most of which are free and can be used by anyone. Despite the services automating most parts of malware analysis, the analyst still requires deep understanding of what he’s looking for in order to understand the service’s output. Dejan Lukan a security researcher for InfoSec Institute takes a look at the output provided by services supporting analysis of PE file formats or Windows executables.
Read the full article here - http://resources.infosecinstitute.com/overview-automated-malware-analysis-cloud/