Microsoft recently had their management summit and there is a lot of buzz around System Center 2012. Tim Mangan took a look at the App-V pieces of System Center Configuration Manager 2012 (beta 2) and wrote a nice article about his findings. Tim states the following in his article:
"SCCM 2012 looks like a real winner to centrally management your application deployments. Microsoft has indicated that it intends to move forward with App-V using both the App-V Management Server and SCCM deployment options for App-V customers. Their intent is that the App-V Management Server, which is a no cost option (in terms of license cost for the App-V Management Server software, you still need an OS and Database Server) is the "good" while SCCM is the "better" option. ...so far [SCCM 2012] looks promising."